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Pyrosequencing Inc multiplex pyrosequencing method
Multiplex Pyrosequencing Method, supplied by Pyrosequencing Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/multiplex+pyrosequencing+method/multiplex+pyrosequencing/pm40640196-568-11-13
Average 90 stars, based on 1 article reviews
multiplex pyrosequencing method - by Bioz Stars, 2026-10
90/100 stars

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Article Title: Population differences in major functional polymorphisms of pharmacokinetics/pharmacodynamics-related genes in Eastern Asians and Europeans: implications in the clinical trials for novel drug development.
Article Snippet: Drug lag, recently discussed extensively in Japan, can be divided into two phases: clinical development time and application review time.. The former factor is still an important problem that might be improved by promoting multi-regional clinical trials and considering the results from other similar populations with Japanese, such as Koreans and Chinese.. In this review, we compare the allelic or genotype frequencies of 30 relatively common functional alleles mainly between Eastern Asians and Europeans as well as among 3 major populations in Eastern Asian countries, Japan, Korea, and China, in 12 pharmacokinetics (PK)/pharmacodynamics (PD)-related genes; CYP2C9 (*2 and *3), CYP2C19 (*2, *3 and *17), 13 CYP2D6 haplotypes including *4, *5 and *10, CYP3A5 (*3), UGT1A1 (*28 and *6), NAT2 (*5, *6 and *7), GSTM1 and GSTT1 null genotypes, SLCO1B1 521T>C, ABCG2 421C>A, and HLAA*31:01 and HLA-B*58:01.

Article Title: CYP2C9, CYP2C19, CYP2D6 and CYP3A5 polymorphisms in South-East and East Asian populations: A systematic review.
Article Snippet: Assessment of CYP2C19 ge‐ netic polymorphisms in a Korean population using a simultaneous multiplex pyrosequencing method to simultaneously detect the CYP2C19*2, CYP2C19*3, and CYP2C19*17 alleles.

Article Title: A narrative review of research advancements in pharmacogenetics of cardiovascular disease and impact on clinical implications.
Article Snippet: Assessment of CYP2C19 genetic polymorphisms in a Korean population using a simultaneous multiplex pyrosequencing method to simultaneously detect the CYP2C19* 2, CYP2C19* 3, and CYP2C19* 17 alleles.

Article Title: Current World Literature
Article Snippet: This bibliography is compiled by clinicians from the journals listed at the end of this publication.. It is based on literature entered into our database between 1 August 2010 and 31 July 2011 (articles are generally added to the database about two and a half months after publication).. In addition, the bibliography contains every paper annotated by reviewers; these references were obtained from a variety of bibliographic databases and published between the beginning of the review period and the time of going to press.

Article Title: Assessment of CYP2C19 genetic polymorphisms in a Korean population using a simultaneous multiplex pyrosequencing method to simultaneously detect the CYP2C19*2, CYP2C19*3, and CYP2C19*17 alleles.
Article Snippet: Background and objective: CYP2C19 is a drugmetabolizing enzyme showing various genetic polymorphisms that may cause marked interindividual and interethnic variability in the disposition of its substrates.. We assessed CYP2C19 genetic polymorphisms in a Korean population using a newly developed multiplex pyrosequencing method.. Method: A multiplex pyrosequencing method to simultaneously detect CYP2C19*2, *3, and *17 alleles was designed.

Article Title: CYP2C19 genetic polymorphism in Saudi Arabians.
Article Snippet: Assessment of CYP2C19 genetic polymorphisms in a Korean population using a simultaneous multiplex pyrosequencing method to simultaneously detect the CYP2C19*2, CYP2C19*3, and CYP2C19*17 alleles.

Article Title: Detection of The Effect of CYP2C19*4 Mutation on Clopidogrel Response by In Silico Methods
Article Snippet: Kim KA, Song WK, Kim KR, Park JY, (2010) Assessment of CYP2C19 genetic polymorphisms in a Korean population using a simultaneous multiplex pyrosequencing method to simultaneously detect the CYP2C19* 2, CYP2C19* 3, and CYP2C19* 17 alleles.

Multiplex Assay:

Article Title: Multiplex pyrosequencing assay using AdvISER-MH-PYRO algorithm: a case for rapid and cost-effective genotyping analysis of prostate cancer risk-associated SNPs
Article Snippet: .. While the added clinical value of MGRS based on 9 PCa risk-associated SNPs proved indeed not bring a major benefit as previously discussed [ ], it was technologically interesting to repeat this SNP analysis using the multiplex pyrosequencing method, especially because this method is widely applicable to a range of other clinical and/or research applications, all relying also on MGRS computation, and therefore requiring multi-SNP genotyping for each patient. ..



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